Score: | 6–3, 6–4 |
See main article: 2012 Mutua Madrid Open. Bob Bryan and Mike Bryan were the defending champions but lost in the second round to Aisam-ul-Haq Qureshi and Jean-Julien Rojer.Mariusz Fyrstenberg and Marcin Matkowski won the tournament defeating Robert Lindstedt and Horia Tecău 6–3, 6–4 in the final.
The top eight seeds receive a bye into the second round.