| Conflict: | Battle of Merv |
| Partof: | the Persian–Uzbek wars |
| Date: | 2 December 1510 |
| Place: | Merv, Khorasan, Turkmenistan |
| Result: | Safavid victory |
| Territory: | Safavids regain control of Khorasan. |
| Combatant1: | Safavid Iran |
| Combatant2: | Khanate of Bukhara |
| Commander1: | Shah Ismail I |
| Commander2: | Muhammad Shaybani |
| Strength1: | 17,000[1] |
| Casualties1: | Unknown |
| Casualties2: | 10,000 Killed |
The Battle of Merv (Persian: نبرد مرو) occurred on 2 December 1510 as a result of the Safavid Persia invasion of the Khorasan region of Uzbek. It ended with Safavids annexation of the Khorasan region.
Shah Ismail reached Khorasan with great speed; Shaybani Khan retreated to Merv castle to await reinforcement from Uzbek tribes. The Safavid army then pretended to retreat, encouraging the Uzbeks to leave the castle in pursuit, only to be ambushed and destroyed by the Qizilbash ("Red Heads") troops of Shah Ismail once they were too far from the castle to regain its safety. The Safavid forces were reportedly heavily outnumbered by the army of Shaybani Khan, who was caught and killed trying to escape the battle. Shah Ismail had his body parts sent to various areas of the empire for display, while famously having his skull coated in gold and made into a jeweled drinking goblet.[2]