DCHS2 explained
Protein dachsous homolog 2, also known as protocadherin-23 (PCDH23) or cadherin-27 (CDH27), is a protein that in humans is encoded by the DCHS2 gene.[1] [2]
DCHS2 has been implicated in the nose angle (how much a nose is upturned).[3] As well as facial genetics [4] [5]
Further reading
- Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8.
- Kimura K, Wakamatsu A, Suzuki Y . Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. . Genome Res. . 16 . 1 . 55–65 . 2006 . 16344560 . 10.1101/gr.4039406 . 1356129. etal.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3. etal.
Notes and References
- Web site: Entrez Gene: dachsous 2 (Drosophila).
- Höng JC, Ivanov NV, Hodor P, Xia M, Wei N, Blevins R, Gerhold D, Borodovsky M, Liu Y . Identification of new human cadherin genes using a combination of protein motif search and gene finding methods . J. Mol. Biol. . 337 . 2 . 307–17 . March 2004 . 15003449 . 10.1016/j.jmb.2004.01.026 .
- A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. 2016. 10.1038/ncomms11616. Adhikari. Kaustubh. Fuentes-Guajardo. Macarena. Quinto-Sánchez. Mirsha. Mendoza-Revilla. Javier. Camilo Chacón-Duque. Juan. Acuña-Alonzo. Victor. Jaramillo. Claudia. Arias. William. Lozano. Rodrigo Barquera. Pérez. Gastón Macín. Gómez-Valdés. Jorge. Villamil-Ramírez. Hugo. Hunemeier. Tábita. Ramallo. Virginia. Silva De Cerqueira. Caio C.. Hurtado. Malena. Villegas. Valeria. Granja. Vanessa. Gallo. Carla. Poletti. Giovanni. Schuler-Faccini. Lavinia. Salzano. Francisco M.. Bortolini. Maria- Cátira. Canizales-Quinteros. Samuel. Cheeseman. Michael. Rosique. Javier. Bedoya. Gabriel. Rothhammer. Francisco. Headon. Denis. González-José. Rolando. Nature Communications. 7. 11616. 27193062. 4874031. 2016NatCo...711616A. 1.
- Web site: Facial Genetics: a Brief Overview.
- Web site: Your nose--Big or small--is shaped by your DNA. . 19 May 2016 .