| James Horace Smith | |
| Office: | 17th Mayor of Orlando |
| Term Start: | 1904 |
| Term End: | 1906 |
| Predecessor: | B. M. Robinson |
| Successor: | Braxton Beacham |
| Birth Date: | 20 October 1852 |
| Occupation: | Physician |
| Spouse: | Martha Philo Smith |
| Children: | Ethel Claire Smith Bumby |
James Horace Smith (October 20, 1852 – June 20, 1931) was an American politician who served as the 17th mayor of Orlando, Florida, from 1904 to 1906. He died at the age of 78 in 1931 and was buried in Greenwood Cemetery.[1]