MatC family explained
The Malonate Uptake (MatC) family (TC# 2.A.101) is a constituent of the ion transporter (IT) superfamily.[1] [2] [3] It consists of proteins from Gram-negative and Gram-positive bacteria (e.g., Xanthomonas, Rhizobium and Streptomyces species), simple eukaryotes (e.g., Chlamydomonas reinhardtii) and archaea (e.g., Methanococcus jannaschii). The proteins are of about 450 amino acyl residues in length with 12-14 putative transmembrane segments (TMSs). Closest functionally-characterized homologues are in the DASS (TC #2.A.47) family. One member of this family is a putative malonate transporter (MatC of Rhizobium leguminosarum bv trifolii, TC# 2.A.101.1.2).[4]
See also
Further reading
- Chen . Wei Ning . Tan . Kee Yang . 2013 . Malonate uptake and metabolism in Saccharomyces cerevisiae . Applied Biochemistry and Biotechnology . 171 . 1. 44–62 . 10.1007/s12010-013-0334-8 . 23813405 . 21408607 .
- Schaffitzel . Christiane . Berg . Michael . Dimroth . Peter . Pos . Klaas M . 1998 . Identification of an Na+-Dependent Malonate Transporter of Malonomonas rubra and Its Dependence on Two Separate Genes . Journal of Bacteriology . 180 . 10. 2689–2693 . 10.1128/JB.180.10.2689-2693.1998 . 107221 . 9573154.
Notes and References
- Lolkema. Juke S.. Slotboom. Dirk Jan. 2003-04-11. Classification of 29 families of secondary transport proteins into a single structural class using hydropathy profile analysis. Journal of Molecular Biology. 327. 5. 901–909. 0022-2836. 12662917. 10.1016/s0022-2836(03)00214-6.
- Prakash. Shraddha. Cooper. Garret. Singhi. Soumya. Saier. Milton H.. 2003-12-03. The ion transporter superfamily. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1618. 1. 79–92. 0006-3002. 14643936. 10.1016/j.bbamem.2003.10.010.
- Rabus. R.. Jack. D. L.. Kelly. D. J.. Saier. M. H.. 1999-12-01. TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters. Microbiology. 145. 3431–3445. 10.1099/00221287-145-12-3431. 1350-0872. 10627041. 12. free.
- Web site: 2.A.101 The Malonate Uptake (MatC) Family (Formerly UIT1). Transporter Classification Database. 2016-03-03.