Ormetoprim Explained

Synonyms:Ormethoprim
Cas Number:6981-18-6
Pubchem:23418
Chemspiderid:21899
Kegg:D05273
Unii:M3EFS94984
Chebi:94553
Chembl:494760
Iupac Name:5-[(4,5-Dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine
Stdinchi:1S/C14H18N4O2/c1-8-4-11(19-2)12(20-3)6-9(8)5-10-7-17-14(16)18-13(10)15/h4,6-7H,5H2,1-3H3,(H4,15,16,17,18)
Stdinchikey:KEEYRKYKLYARHO-UHFFFAOYSA-N
Smiles:CC1=CC(=C(C=C1CC2=CN=C(N=C2N)N)OC)OC
C:14
H:18
N:4
O:2

Ormetoprim is an antibiotic used in veterinary medicine. Typically it is used in combination with sulfadimethoxine, and it is used in the poultry[1] and aquaculture industries.[2]

Ormetoprim, like other diaminopyrimidines such as trimethoprim, inhibits the reduction of dihydrofolic acid to tetrahydrofolic acid by bacterial cells.[3]

Notes and References

  1. Book: 10.1002/9781118675014.ch34 . Antimicrobial Drug Use in Poultry . Antimicrobial Therapy in Veterinary Medicine . 2013 . Hofacre CL, Fricke JA, Inglis T . 569–587 . 978-0-470-96302-9 .
  2. Singh M, Singh P . Drugs and chemicals applied in aquaculture industry: A review of commercial availability, recommended dosage and mode of application . Journal of Entomology and Zoology Studies . 2018 . 6 . 6 . 903–907 .
  3. Web site: PRIMOR - sulfadimethoxine and ormetoprim tablet . DailyMed . U.S. National Library of Medicine .