| Sébaco | |
| Settlement Type: | Municipality |
| Pushpin Map: | Nicaragua |
| Pushpin Label Position: | right |
| Pushpin Mapsize: | 250 |
| Pushpin Map Caption: | Location in Nicaragua |
| Subdivision Type: | Country |
| Subdivision Name: |  Nicaragua |
| Subdivision Type1: | Department |
| Subdivision Name1: | Matagalpa |
| Leader Title: | Mayor |
| Leader Name: | Luis Martínez Medal |
| Unit Pref: | Imperial |
| Area Total Km2: | 290 |
| Population As Of: | 2022 estimate |
| Population Footnotes: | [1] |
| Population Total: | 38296 |
| Population Density Km2: | auto |
| Population Urban: | 25763 |
| Coordinates: | 12.85°N -92°W |
| Blank Name: | Climate |
| Blank Info: | Aw |
Sébaco is a town and a municipality in the Matagalpa department of Nicaragua. Situated at the junction of the Pan-American Highway and the Rio Grande de Matagalpa, Sébaco is the largest city of the agricultural Sébaco Valley, one of the most fertile areas in Nicaragua. From Sébaco, vegetable fields extend beyond the horizon when looking west. Five kilometres north of the city, a highway branches east from the Pan-American towards the city of Matagalpa.
King Charles I of Spain named the area "The Very Noble City of Sébaco" by decree. In 2006 the National Assembly of Nicaragua officially named the city Sébaco. The name Sébaco originates from the Nawat language that the Nicarao people spoke who still inhabit the Sébaco Valley. It derives from Siwakuat, which means snake woman. Cihuacoatl was also the Aztec goddess of fertility and agriculture. When the Spanish arrived in the area, they were unable to pronounce the original name of this town, and due to their Tlaxcalan interpreters speaking Nahuatl, it was wrongly documented and over time the pronunciation became Sébaco.[2]