S-formylglutathione hydrolase explained
S-formylglutathione hydrolase |
Ec Number: | 3.1.2.12 |
Cas Number: | 50812-21-0 |
Go Code: | 0018738 |
The enzyme S-formylglutathione hydrolase (EC 3.1.2.12) catalyzes the reaction
S-formylglutathione + H2O
glutathione + formate
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is S-formylglutathione hydrolase. It participates in Methane Metabolism.
References
- Uotila L . 1973 . Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases . Biochemistry . 12 . 3938 - 43 . 4200890 . 10.1021/bi00744a024 . 20 .
- Uotila L, Koivusalo M . 1974 . Purification and properties of S-formylglutathione hydrolase from human liver . J. Biol. Chem. . 249 . 7664 - 72 . 4436331 . 23 .
- Harms N, Ras J, Reijnders WN, van Spanning RJ, Stouthamer AH . 1996 . S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification? . J. Bacteriol. . 178 . 6296 - 9 . 8892832 . 21 . 178503 .