Stefan D. Anker Explained

Stefan D. Anker
Birth Place:Berlin
Nationality:German
Fields:Cardiology, heart failure, muscle wasting, cachexia, sarcopenia, treatment development, drugs & devices, clinical trials
Workplaces:University Medical Center, Göttingen
Alma Mater:Humboldt University Berlin, Imperial College London
Known For:Researching heart failure

Stefan D. Anker is a German cariologist who is Head of Field “Tissue Homeostasis and Cachexia" at Charité University, Berlin, Germany.[1] Previously, he was Professor of Innovative Clinical Trials at University Medical Center Göttingen in Germany.[2] The main focus of the Innovative Clinical Trials department was research in the field of chronic heart failure, including the development and clinical testing of new therapies.[3]

Education

Anker studied medicine at Charité Medical School of Humboldt-University Berlin, Germany (1987-1993)[1] and completed his PhD at the National Heart and Lung Institute of Imperial College London, United Kingdom, in 1998.

Career and research

Anker has had teaching appointments in the UK, Germany, Australia and Italy.[4]

His particular research interests include the pathophysiology and treatment of acute and chronic heart failure (CHF), cardiac device therapy, clinical evaluation of cardiovascular biomarkers, pathophysiology of muscle wasting, cachexia therapy[5] in CHF, ageing, sarcopenia and cancer.[6]

Anker serves on the editorial boards of European Heart Journal[7] and European Journal of Heart Failure.[8] He is founding Editor-in-Chief of the Journal of Cachexia, Sarcopenia and Muscle[9] and of ESC Heart Failure, which is the first open access heart failure journal.[10]

Anker has won two American Heart Association Young Investigator Awards[11] [12] and has obtained two National Institutes of Health (NIH) grants (Warfarin Versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) Trial),[13] two grants from the EU's Seventh Framework Programme for Research (FP7), and one Innovative Medicines Initiative / Horizon 2020 grant.[14]

Memberships

Anker has been a member of the German Cardiac Society and of the European Society of Cardiology (ESC) since 1995. He is currently vice president of the ESC in charge of 'National Cardiac Societies and Communications.' He has been serving on the board of the ESC since 2012.[15] In addition, he has been serving on the board of the Heart Failure Association (HFA) of the ESC since 2006. He was HFA President between 2012 and 2014 and he chairs the HFA committee on regulatory affairs.[16]

Anker is the founding president of the International Society on Sarcopenia, Cachexia and Wasting Disorders (SCWD).[17] [18]

Selected publications

Anker has authored more than 700 original papers, reviews, and editorials. Total citations exceed 46,000, including over 50 papers with more than 200 citations. He has an h-index of 104.[19]

Consensus meetings and guidelines

Anker has participated in and chaired several consensus meeting and guidelines committees:

Research

Anker has been a member of more than 30 international clinical trial steering committees, chairing or co-chairing more than 10 (including the FAIR-HF,[33] TIM-HF,[34] BACH,[35] AUGMENT-HF,[36] ACT-ONE,[37] RESHAPE-HF2,[38] IMPULSE-HF,[39] FAIR-HF2,[40] [41] Fair-HFpEF,[41] EMPORER-HFpEF trials[42]). He served in several data and safety monitoring boards (chairing five) and end-point committees (chairing three).[14] In 2015 and again in 2016, he was named in the Thomson Reuters Highly Cited Researchers list.[43]

Honors and awards

2018: Copernicus Award from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) and the Fundacja na rzecz Nauki Polskiej (FNP, Foundation for Polish Science)[45] for services to German-Polish research collaboration[46]

Notes and References

  1. Web site: BCRT / Single News / Berlin-Brandenburger Centrum für Regenerative Therapien. www.b-crt.de. de. 2017-10-04.
  2. Web site: Universitätsmedizin Göttingen - Scientific staff. www.herzzentrum-goettingen.de. 2017-05-17.
  3. Web site: Universitätsmedizin Göttingen - Innovative Clinical Trials. www.herzzentrum-goettingen.de. 2017-05-17.
  4. News: ICI Meeting 2016 Staff Members Stefan D. Anker Innovations. 2017-05-17. en-US.
  5. News: This Potentially Fatal Syndrome Makes Your Body Literally Waste Away—And It's More Common Than You Know. 2017-09-27. Prevention. 2017-10-04. en.
  6. Web site: Journal of Cachexia, Sarcopenia and Muscle. Wiley Online Library.
  7. Web site: European Heart Journal . 2024-06-21 . academic.oup.com.
  8. Web site: European Journal of Heart Failure. 10.1002/(ISSN)1879-0844. 115560449.
  9. Web site: Home. www.jcsm.info. en-gb. 2017-05-17.
  10. ESC Heart Failure . ESC Heart Failure . en . 10.1002/(issn)2055-5822. free .
  11. AHA Samuel A Levine Young Investigator Award (Clinical Cardiology) 1st Prize for the paper: Sharma R, Coats AJS, Anker SD. Cellular endotoxin desensitization in patients with severe chronic heart failure, November 2000.
  12. AHA Samuel A Levine Young Investigator Award (Clinical Cardiology) 1st Prize; for the paper: Okonko D, Poole-Wilson PA, Anker SD, Ponikowski P. Intravenous iron therapy in patients with chronic heart failure with and without anemia, November 2006.
  13. Warfarin Versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) Trial . Homma . Shunichi . 2014-08-29 . clinicaltrials.gov . NCT00041938.
  14. Web site: HFA Career Cafe 2017. www.escardio.org. 2017-05-17.
  15. Web site: ESC Board. www.escardio.org. 2017-05-17.
  16. Web site: Committees and Study Groups of the Heart Failure Association of the ESC. www.escardio.org. 2017-05-17.
  17. News: Details of the SCWD board members. Sarcopenia, Cachexia and Wasting Disorders. 2017-05-17. en-GB.
  18. News: SCWD - Sarcopenia, Cachexia and Wasting Disorders. Sarcopenia, Cachexia and Wasting Disorders. 2017-05-17. en-GB.
  19. Scopus, March 2017, https://www.scopus.com/authid/detail.uri?authorId=56223993400
  20. Evans. William J.. Morley. John E.. Argilés. Josep. Bales. Connie. Baracos. Vickie. Guttridge. Denis. Jatoi. Aminah. Kalantar-Zadeh. Kamyar. Lochs. Herbert. 2008-12-01. Cachexia: a new definition. Clinical Nutrition (Edinburgh, Scotland). 27. 6. 793–799. 10.1016/j.clnu.2008.06.013. 1532-1983. 18718696. 206821612 .
  21. Riegel. Barbara. Moser. Debra K.. Anker. Stefan D.. Appel. Lawrence J.. Dunbar. Sandra B.. Grady. Kathleen L.. Gurvitz. Michelle Z.. Havranek. Edward P.. Lee. Christopher S.. 2009-09-22. State of the science: promoting self-care in persons with heart failure: a scientific statement from the American Heart Association. Circulation. 120. 12. 1141–1163. 10.1161/CIRCULATIONAHA.109.192628. 1524-4539. 19720935. 10.1.1.335.9667. 6973440 .
  22. Ronco. Claudio. McCullough. Peter. Anker. Stefan D.. Anand. Inder. Aspromonte. Nadia. Bagshaw. Sean M.. Bellomo. Rinaldo. Berl. Tomas. Bobek. Ilona. 2017-05-17. Cardio-renal syndromes: report from the consensus conference of the Acute Dialysis Quality Initiative. European Heart Journal. 31. 6. 703–711. 10.1093/eurheartj/ehp507. 0195-668X. 2838681. 20037146.
  23. Argilés. Josep M.. Anker. Stefan D.. Evans. William J.. Morley. John E.. Fearon. Ken C. H.. Strasser. Florian. Muscaritoli. Maurizio. Baracos. Vicky E.. 2010-05-01. Consensus on cachexia definitions. Journal of the American Medical Directors Association. 11. 4. 229–230. 10.1016/j.jamda.2010.02.004. 1538-9375. 20439040.
  24. Morley. John E.. Argiles. Josep M.. Evans. William J.. Bhasin. Shalender. Cella. David. Deutz. Nicolaas E. P.. Doehner. Wolfram. Fearon. Ken C. H.. Ferrucci. Luigi. 2017-05-17. Nutritional Recommendations for the Management of Sarcopenia. Journal of the American Medical Directors Association. 11. 6. 391–396. 10.1016/j.jamda.2010.04.014. 1525-8610. 4623318. 20627179.
  25. Fearon. Kenneth. Strasser. Florian. Anker. Stefan D.. Bosaeus. Ingvar. Bruera. Eduardo. Fainsinger. Robin L.. Jatoi. Aminah. Loprinzi. Charles. MacDonald. Neil. 2011-05-01. Definition and classification of cancer cachexia: an international consensus. The Lancet. Oncology. 12. 5. 489–495. 10.1016/S1470-2045(10)70218-7. 1474-5488. 21296615.
  26. McMurray. John J. V.. Adamopoulos. Stamatis. Anker. Stefan D.. Auricchio. Angelo. Böhm. Michael. Dickstein. Kenneth. Falk. Volkmar. Filippatos. Gerasimos. Fonseca. Cândida. 2012-07-01. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. European Heart Journal. 33. 14. 1787–1847. 10.1093/eurheartj/ehs104. 1522-9645. 22611136. free.
  27. Lip. Gregory Y. H.. Ponikowski. Piotr. Andreotti. Felicita. Anker. Stefan D.. Filippatos. Gerasimos. Homma. Shunichi. Morais. Joao. Pullicino. Patrick. Rasmussen. Lars H.. 2012-07-01. Thrombo-embolism and antithrombotic therapy for heart failure in sinus rhythm. A joint consensus document from the ESC Heart Failure Association and the ESC Working Group on Thrombosis. European Journal of Heart Failure. 14. 7. 681–695. 10.1093/eurjhf/hfs073. 1879-0844. 22611046. 20956860. free.
  28. Mancia. Giuseppe. Fagard. Robert. Narkiewicz. Krzysztof. Redon. Josep. Zanchetti. Alberto. Böhm. Michael. Christiaens. Thierry. Cifkova. Renata. De Backer. Guy. 2013-07-01. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal. 34. 28. 2159–2219. 10.1093/eurheartj/eht151. 1522-9645. 23771844. free. 1854/LU-4127523. free.
  29. Authors/Task Force Members. Rydén. Lars. Grant. Peter J.. Anker. Stefan D.. Berne. Christian. Cosentino. Francesco. Danchin. Nicolas. Deaton. Christi. Escaned. Javier. 2013-10-01. ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: the Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collaboration with the European Association for the Study of Diabetes (EASD). European Heart Journal. 34. 39. 3035–3087. 10.1093/eurheartj/eht108. 1522-9645. 23996285. free.
  30. Kristensen. Steen Dalby. Knuuti. Juhani. Saraste. Antti. Anker. Stefan. Bøtker. Hans Erik. Hert. Stefan De. Ford. Ian. Gonzalez-Juanatey. Jose Ramón. Gorenek. Bulent. 2014-09-14. 2014 ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management: The Joint Task Force on non-cardiac surgery: cardiovascular assessment and management of the European Society of Cardiology (ESC) and the European Society of Anaesthesiology (ESA). European Heart Journal. 35. 35. 2383–2431. 10.1093/eurheartj/ehu282. 1522-9645. 25086026. free.
  31. Anker. Stefan D.. Agewall. Stefan. Borggrefe. Martin. Calvert. Melanie. Jaime Caro. J.. Cowie. Martin R.. Ford. Ian. Paty. Jean A.. Riley. Jillian P.. 2014-08-07. The importance of patient-reported outcomes: a call for their comprehensive integration in cardiovascular clinical trials. European Heart Journal. 35. 30. 2001–2009. 10.1093/eurheartj/ehu205. 1522-9645. 24904027. free.
  32. Ponikowski. Piotr. Voors. Adriaan A.. Anker. Stefan D.. Bueno. Héctor. Cleland. John G. F.. Coats. Andrew J. S.. Falk. Volkmar. González-Juanatey. José Ramón. Harjola. Veli-Pekka. 2016-07-14. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. European Heart Journal. 37. 27. 2129–2200. 10.1093/eurheartj/ehw128. 1522-9645. 27206819. free.
  33. Web site: FAIR-HF - Wiki Journal Club. LLC. Peripheral Brain. www.wikijournalclub.org. en. 2017-05-17.
  34. 10.1093/eurjhf/hfq199 . 21098580 . 12 . 12 . Telemedical Interventional Monitoring in Heart Failure (TIM-HF), a randomized, controlled intervention trial investigating the impact of telemedicine on mortality in ambulatory patients with heart failure: study design . European Journal of Heart Failure . 1354–1362 . Koehler . Friedrich . 2010. 32860744 . free .
  35. Biomarkers in Acute Heart Failure - Full Text View - ClinicalTrials.gov. clinicaltrials.gov. 30 July 2008 . en. 2017-05-17.
  36. Anker. Stefan D.. Coats. Andrew J. S.. Cristian. Gabriel. Dragomir. Dinu. Pusineri. Enrico. Piredda. Massimo. Bettari. Luca. Dowling. Robert. Volterrani. Maurizio. 2015-09-07. A prospective comparison of alginate-hydrogel with standard medical therapy to determine impact on functional capacity and clinical outcomes in patients with advanced heart failure (AUGMENT-HF trial). European Heart Journal. 36. 34. 2297–2309. 10.1093/eurheartj/ehv259. 1522-9645. 4561351. 26082085.
  37. Rosenfield. Kenneth. Matsumura. Jon S.. Chaturvedi. Seemant. Riles. Tom. Ansel. Gary M.. Metzger. D. Chris. Wechsler. Lawrence. Jaff. Michael R.. Gray. William. 2016-03-17. Randomized Trial of Stent versus Surgery for Asymptomatic Carotid Stenosis. New England Journal of Medicine. 374. 11. 1011–1020. 10.1056/NEJMoa1515706. 0028-4793. 26886419. free.
  38. Web site: A Clinical Evaluation of the Safety and Effectiveness of the MitraClip System in the Treatment of Clinically Significant Functional Mitral Regurgitation - Full Text View - ClinicalTrials.gov. clinicaltrials.gov. en. 2017-05-17.
  39. Web site: Impulse Dynamics announced the first enrollment in the IMPULSE-HF European Randomized Efficacy Study - INT. www.impulse-dynamics.com. en-INT. 2017-05-17.
  40. Web site: Clinical Trials Register. www.clinicaltrialsregister.eu. 2017-05-17.
  41. Web site: Universitätsmedizin Göttingen - Innovative Clinical Trials. www.herzzentrum-goettingen.de. 2017-05-17.
  42. Web site: EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved) - Full Text View - ClinicalTrials.gov. clinicaltrials.gov. en. 2017-05-17.
  43. News: HCR Clarivate Analytics. 2017-05-17. en.
  44. Council on Clinical Cardiology: Scientific Sessions 2006 Highlights . November 2006 . 19 . https://web.archive.org/web/20161020181657/http://www.heart.org/idc/groups/ahamah-public/@wcm/@sop/documents/downloadable/ucm_319457.pdf . 2016-10-20.
  45. https://www.fnp.org.pl/en/laureaci-nagrody-copernicus-2018/
  46. News: Copernicus Award 2018 for Stefan Anker. 2018-11-08. en.